Research Associate, Assay Development

Responsibilities:

• Conducts routine and non-routine lab procedures and assays for molecular, cellular, and metabolic characterization of relevant samples from mouse models of cancer and human clinical cancer tissue.
• This includes the conduct of relevant exploratory experiments and control experiments, applying basic scientific principles.
• As needed, supports the development and validation of new technologies for molecular, cellular and metabolic characterization of samples.
• Supports the development of biological, immunological assays to investigate mechanisms of immune-mediated effects of novel identified targets.
• Contributes to the profiling and validation of novel, druggable, immunotherapy targets.
• Documents and maintains a detailed and precise record of work performed.
• Performs lab management, which includes ordering supplies and maintaining inventory, ensuring safety, service and maintain laboratory instruments of the lab,etc
• Actively participates in the scientific dialogue of the group and proactively collaborates with colleagues
• Performs all other duties as assigned

Qualifications:

• Master’s Degree from an accredited institution or bachelor’s degree from an accredited institution and 1 year lab experience either in industry or academic lab required.
• Prior biopharma industry or commercial research experience desired experience with several of the following relevant techniques:
  • Mammalian cell culture
  • Flow cytometry and cell sorting
  • Molecular biology techniques (e.g., PCR, development of genetic constructs, cloning, etc.)
  • NGS (WGS, WES or RNAseq, including preparation of genomic libraries)
  • CRISPR or other advanced genetic editing techniques
  • Processing and characterization of fresh human tumor samples
  • Cell-based metabolic assays
• Ability to propose new experimental designs, plan and conduct laboratory experiments, and evaluate and interpret data.
• Fundamental understanding of the process of discovery and development of immunology-based therapeutic targets and possible novel therapeutic concepts
• Experience in immuno-oncology-related animal studies is a plus
• The role requires critical thinking e.g. by proposing and implementing novel experimental approaches and concepts contributing to cancer immunology and immune therapy research goals.
• The ideal candidate is product and goal oriented, focused on a career in biotech. They are highly efficient and organized and have a demonstrated ability to adheres to and follow defined timelines, milestone, and objectives.
• Experience in working under GLP standards and ensuring safety compliance under BSL-2.
• Experience with laboratory information system (LIMS) is a plus
• Good verbal and written communication skills and the ability to interpret, summarize, and present results in a clear, concise, accurate manner

• Environmental Conditions
  • Sedentary

• Physical Demands
  • Sedentary